01 - Preheat oven to 400°F. Line a baking sheet with parchment paper.
02 - In a skillet over medium heat, sauté the diced onion until translucent, about 3 minutes. Add ground beef, garlic powder, salt, and black pepper. Cook, breaking up meat, until browned throughout. Drain excess fat.
03 - Stir ketchup, yellow mustard, Worcestershire sauce, and chopped pickles into the cooked beef mixture. Remove skillet from heat and allow the filling to cool slightly.
04 - Flatten each biscuit into a round disc. Place 1 tablespoon of beef mixture in the center of each dough round, add 1/2 tablespoon shredded cheddar, and top with a mozzarella cube.
05 - Encase the filling by gathering dough edges and pinching to fully seal, shaping into a smooth ball. Place each on the prepared baking sheet, seam side down.
06 - Brush each dough ball with beaten egg using a pastry brush. Sprinkle tops with sesame seeds.
07 - Bake in the preheated oven for 15 to 18 minutes, or until the exterior is deeply golden brown.
08 - Let bombs cool slightly before serving. Pair with extra burger sauces for dipping if desired.